What are some general contraindications for kidney transplantation from a recipient perspective?
• Presence of vascular disease that precludes the arterial and venous anastomoses requisite for a technically successful transplant
• Recent or current malignancy
Data from Penn, I. (1993). The effect of immunosuppression on pre-existing cancers. Transplantation, 55 , 742–747.Guidelines for Transplantation in Patients With Previous Malignancies
Generally: Advised waiting time is 2 years
No waiting time necessary:
Incidental renal carcinoma
In situ carcinoma
Focal neoplasm (defined as a localized tumor without metastases)
Low-grade bladder cancer
Basal cell skin cancer
Waiting time of more than 2 years necessary:
Melanoma
Breast carcinoma
Colorectal carcinoma
Uterine carcinoma
• Chronic illness with short life expectancy
• Active substance abuse
• Active infectious process
• Poor cardiac and pulmonary status
• Psychosocial factors that may hinder future medicine adherence
