What are some causes of chronic airspace disease?
- Malignancy (lymphoma
- Bronchoalveolar subtype lung cancer)
- Organizing pneumonia
- Mycobacterial and fungal infections
- Chronic eosinophilic pneumonia, and
- PAP
Airspace disease can be acute or chronic and commonly present as consolidation or ground-glass opacity on chest imaging.
Consolidation or ground-glass opacity occurs when alveolar air is replaced by fluid, pus, blood, cells, or other material.
Airspace disease is considered chronic when it persists beyond 4-6 weeks after treatment. These can be secondary to certain infectious, inflammatory, or neoplastic conditions.
Computed tomography of the chest is usually performed in this set of patients to identify characteristic imaging findings.
Familiarity with the differential diagnosis and characteristic imaging findings for chronic airspace disease is very important for guiding patient’s management in a timely fashion.
