Can any treatment prevent attacks of acute CPP arthritis from occurring?
Fortunately, most patients only have a few attacks that are widely separated in time, and thus require no prophylaxis against pseudogout. For patients with frequent attacks, colchicine at 0.6 mg once or twice a day may help reduce the rate of subsequent attacks/flares. Other approaches include daily low-dose NSAIDs or low-dose prednisone, although data regarding efficacy is limited.
