Basic Calcium Phosphate and Other Crystalline Diseases
1. Basic calcium phosphate (BCP) crystals can deposit in joints, muscles, and periarticular soft tissues and occur most commonly in the shoulder tendons/bursa.
2. BCP crystal deposits can remain asymptomatic or shed, causing acute calcific periarthritis.
3. BCP crystals are involved in the pathogenesis of a large joint destructive arthritis such as Milwaukee shoulder syndrome and may contribute to osteoarthritis (OA) in other joints.
