Are antibiotics effective in shiga toxin infection

Are antibiotics effective in shiga toxin infection

Should patients with shiga toxin infection be treated with antibiotics?

No. This has remained a controversial subject for many years. A recent meta-analysis revealed that the use of antibiotics in Shiga toxin infections was not associated with increased risk of developing HUS.

When the authors excluded papers that were at a high risk of bias and did not have an acceptable definition of HUS, there was a significant association between antibiotic use for Shiga toxin infections and the development of HUS.

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