Acute diarrhea in immunocompromised

What specific unique etiologic factors exist for acute diarrheal illness in immunocompromised hosts? 

  • Immunoglobulin A deficiency, human immunodeficiency virus (HIV) and acquired immune deficiency syndrome, organ transplantation, rheumatologic disease on immune-suppressing agents, and chemotherapy all may predispose individuals to enteric infection.
  • These hosts are susceptible to common causes of acute diarrhea but also to agents not commonly problematic for normal hosts: Mycobacteria, Cyclospora, Isospora Cryptosporidium , cytomegalovirus (CMV), and herpes.
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