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Olopatadine Brand Names
Pataday | Patanase | Patanol | Pazeo
What is Olopatadine
Olopatadine is a topical antihistamine with selective H1-receptor antagonist activity and mast cell stabilizing effects.
It is marketed as an ophthalmic agent for the prevention of ocular pruritus due to allergic conjunctivitis and as a nasal spray for the relief of the symptoms of seasonal allergic rhinitis.
The ophthalmic solution is available as an over-the-counter 0.1% and 0.2% solution and as a prescription-only 0.7% solution.
Although no comparative studies have been performed, olopatadine may be a more potent mast cell stabilizer than cromolyn.
Indications
- allergic conjunctivitis
- allergic rhinitis
- ocular pruritus
- seasonal allergies
For the treatment of the signs and symptoms of allergic conjunctivitis, including ocular pruritus
Side Effects
- anosmia
- asthenia
- back pain
- blepharedema
- blurred vision
- conjunctivitis
- cough
- depression
- diarrhea
- drowsiness
- dysgeusia
- epistaxis
- fatigue
- fever
- foreign body sensation
- headache
- hyperemia
- infection
- influenza
- keratitis
- nasal septum perforation
- nausea
- ocular irritation
- ocular pruritus
- pharyngitis
- rash
- rhinitis
- rhinorrhea
- sinusitis
- throat irritation
- wheezing
- xerophthalmia
- xerostomia
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- breast-feeding
- children
- contact lenses
- depression
- driving or operating machinery
- geriatric
- infants
- nasal septal perforation
- nasal trauma
- neonates
- pregnancy
Interactions
- Ethanol
Ethanol: (Moderate) Caution should be used when olopatadine nasal spray is used in combination with CNS depressants like ethanol. Patients should be advised to limit ethanol ingestion while taking olopatadine nasal spray; increased drowsiness may occur.
