What's on this Page
Isoxsuprine Brand Names- Tri Soxsuprine | Vasodilan
What is Isoxsuprine
Isoxsuprine is a vasodilator that acts primarily on blood vessels within skeletal muscle.
It is used for cerebral and peripheral vascular insufficiency.
The FDA has listed isoxsuprine as being ‘possibly effective’ for its labeled indications; the drug has been designated a Level 5 on the DESI Less-Than-Effective drug list.
Isoxsuprine may treat the symptoms of conditions such as arteriosclerosis obliterans,
Raynaud’s phenomenon and thromboangiitis obliterans (Buerger’s disease). Isoxsuprine also has unlabeled uses for dysmenorrhea and premature labor. The use of isoxsuprine for the management of impotence is considered investigational.
In the US, isoxsuprine is only commercially available as oral tablets. A parenteral formulation is found outside the US.
The FDA approved isoxsuprine in 1959.
Indications
- cerebrovascular insufficiency
- dysmenorrhea
- peripheral vascular disease (PVD)
- premature labor
- Raynaud’s phenomenon
For the treatment of cerebrovascular insufficiency and peripheral vascular disease (PVD) such as Raynaud’s phenomenon
Side Effects
- abdominal pain
- anaphylactoid reactions
- chest pain (unspecified)
- dizziness
- hypotension
- nausea
- pulmonary edema
- rash
- sinus tachycardia
- urticaria
- vomiting
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- acute myocardial infarction
- asthma
- bleeding
- breast-feeding
- cardiac arrhythmias
- cardiac disease
- cerebrovascular disease
- children
- chorioamnionitis
- coronary artery disease
- diabetes mellitus
- driving or operating machinery
- eclampsia
- fetal distress
- geriatric
- glaucoma
- heart failure
- hyperthyroidism
- hypotension
- intrauterine fetal death
- labor
- preeclampsia
- pregnancy
- pulmonary hypertension
- thyroid disease
- thyrotoxicosis
- vaginal bleeding
Interactions
There are no drug interactions associated with Isoxsuprine products.
