Fluorometholone

Fluorometholone Brand Names

Eflone | Flarex | Fluor-Op | FML | FML Forte | FML Forte S.O.P.

What is Fluorometholone

Fluorometholone is a synthetic fluorinated corticosteroid that is structurally related to progesterone.

It is indicated for treating corticosteroid-responsive allergic and inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe.

Fluorometholone is one of three ophthalmic corticosteroids preferred for long-term treatment because it is less likely to increase intraocular pressure.

Fluorometholone was approved by the FDA in July 1982.

Indications

  1. allergic conjunctivitis
  2. giant papillary conjunctivitis (GPC)
  3. keratitis
  4. ocular burns
  5. postoperative ocular inflammation
  6. uveitis
  7. vernal keratoconjunctivitis

For the treatment of corticosteroid-responsive ophthalmic disorders including allergic conjunctivitis, ocular burns or trauma due to corneal injury resulting from chemical, thermal or penetration trauma, giant papillary conjunctivitis (GPC), keratitis, postoperative ocular inflammation, vernal keratoconjunctivitis, and chronic anterior uveitis

Side Effects

  1. blepharedema
  2. blepharitis
  3. blurred vision
  4. cataracts
  5. conjunctival hyperemia
  6. conjunctivitis
  7. foreign body sensation
  8. hyperemia
  9. impaired wound healing
  10. keratoconjunctivitis
  11. lacrimation
  12. mydriasis
  13. ocular discharge
  14. ocular hypertension
  15. ocular infection
  16. ocular inflammation
  17. ocular irritation
  18. ocular pain
  19. ocular pruritus
  20. ptosis
  21. rash
  22. uveitis
  23. visual impairment

Monitoring Parameters

  • ophthalmologic exam

Contraindications

  • breast-feeding
  • children
  • contact lenses
  • fungal infection
  • glaucoma
  • herpes infection
  • herpes simplex keratitis (dendritic keratitis)
  • infants
  • mycobacterial infection
  • neonates
  • pregnancy
  • varicella
  • viral infection

Interactions

There are no drug interactions associated with Fluorometholone products.

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