Factor 13 Concentrate Brand Name– Corifact
What is Factor 13 Concentrate
Factor 13 Concentrate is a heat-treated, lyophilized coagulation factor 13 concentrate made from pooled human plasma.
It is approved for the prevention of bleeding episodes in patients with congenital factor XIII deficiency.
Factor 13 Concentrate was approved by the FDA in February 2011.
Indications & Dosage
- factor 13 deficiency
For routine bleeding prophylaxis in patients with congenital factor 13 deficiency
NOTE: Factor 13 concentrate has not been proven to have a direct benefit on the treatment of bleeding episodes.
Side Effects
- abdominal pain
- anaphylactoid reactions
- antibody formation
- arthralgia
- chills
- diarrhea
- dyspnea
- elevated hepatic enzymes
- epistaxis
- erythema
- fever
- headache
- hematoma
- infection
- nausea
- pruritus
- rash
- thromboembolism
- thrombosis
- vomiting
Monitoring Parameters
- factor XIII concentrations
Contraindications
- breast-feeding
- factor XIII inhibitors
- infection
- labor
- obstetric delivery
- pregnancy
- thromboembolic disease
Interactions
- Factor 7a, Recombinant
