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Etidocaine Brand Name
What is Etidocaine
NOTE: This drug is discontinued in the US.
Etidocaine is a long-acting local anesthetic of the amide type. It is used for epidural, local, and retrobulbar anesthesia in surgical and dental procedures.
Like lidocaine, it has a rapid onset of sensory and motor blockade, but duration of analgesia is 1.5—2 times longer than lidocaine when given peridurally.
This difference is greater following peripheral nerve block, when duration of analgesia in excess of 9 hours is common.
Etidocaine produces profound motor blockade and muscle relaxation when used for peridural analgesia.
Etidocaine is available as parenteral injection with or without epinephrine. It received FDA approval in 1976.
Etidocaine products, with or without epinephrine, were removed from the US market in 2001.
Indications
- Caesarean section anesthesia
- central neural block
- epidural anesthesia
- inferior alveolar nerve block
- infiltration anesthesia
- intraabdominal anesthesia
- local anesthesia
- lower limb anesthesia
- maxillary nerve block
- ophthalmic anesthesia
- pelvic anesthesia
- peripheral nerve block
- regional anesthesia
- retrobulbar nerve block
Side Effects
- anaphylactoid reactions
- angina
- anxiety
- atrial fibrillation
- AV block
- back pain
- bradycardia
- cardiac arrest
- decreased uterine contractility
- dizziness
- drowsiness
- fetal acidosis
- fetal bradycardia
- headache
- hypotension
- injection site reaction
- nausea
- neonatal depression
- palpitations
- PR prolongation
- pruritus
- QT prolongation
- rash
- respiratory depression
- restlessness
- seizures
- shivering
- tremor
- trismus
- urticaria
- visual impairment
- vomiting
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- amide local anesthetic hypersensitivity
- anticoagulant therapy
- AV block
- breast-feeding
- cardiac disease
- children
- coagulopathy
- dehydration
- eclampsia
- fetal distress
- fetal prematurity
- geriatric
- head and neck anesthesia
- heart failure
- hepatic disease
- hypertension
- hypotension
- hypovolemia
- infection
- intraarterial administration
- intrathecal administration
- intravenous administration
- labor
- myasthenia gravis
- neurological disease
- obstetric delivery
- ocular surgery
- paracervical nerve block
- pregnancy
- pudendal nerve block
- QT prolongation
- sepsis
- shock
- thrombocytopenia
Interactions
No information is available regarding drug interactions associated with Etidocaine