Emerging osteoporosis therapies in development

What new and emerging osteoporosis therapies are in development?

  • • Antiresorptive drugs
    • • New SERMs: lasofoxifene, bazedoxifene, arzoxifene
  • • Osteoanabolic drugs
    • • Teriparatide: transdermal, intranasal
    • • Abaloparatide: transdermal
    • • Sclerostin inhibitors: antisclerostin antibody (romosozumab)
    • • Calcilytic (stimulates endogenous PTH release): ronacaleret
    • • Tryptophan hydroxylase 1 (Tph 1) inhibitor: inhibit gut-derived serotonin
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