What's on this Page
Butenafine Brand Names
Lotrimin | Mentax | Mentax -TC
What is Butenafine
Butenafine is a topical antifungal agent. Butenafine is a benzylamine antifungal derivative, which is structurally similar to the allylamines (e.g., naftifine and terbinafine).
Butenafine is active against a variety of superficial dermatophytes responsible for causing tinea pedis, tinea corporis, and tinea cruris.
The products contain 10 mg butenafine HCl per gram of the cream vehicle. The FDA approved butenafine in October 1996.
Indications
- Candida albicans
- Candida sp.
- Epidermophyton floccosum
- Malassezia furfur
- Microsporum canis
- tinea corporis
- tinea cruris
- tinea pedis
- tinea versicolor
- Trichophyton mentagrophytes
- Trichophyton rubrum
- Trichophyton tonsurans
- Trichophyton violaceum
Side Effects
- contact dermatitis
- erythema
- pruritus
- skin irritation
Topical administration of butenafine cream is associated with local adverse effects (< 2%), which most commonly include pruritus, burning, skin irritation, contact dermatitis, and erythema.
Other adverse events reported in approximately 1% of patients include burning, stinging, and worsening of the condition.
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- breast-feeding
- children
- infants
- neonates
- ocular exposure
- onychomycosis
- ophthalmic administration
- pregnancy
- vaginal administration
Interactions
There are no drug interactions associated with Butenafine products.
