Beclomethasone

Beclomethasone Brand Names

Beclovent | Beconase AQ | Qnasl | Qnasl Children’s | QVAR | Vancenase | Vancenase AQ | Vanceril

What is Beclomethasone

Beclomethasone is a synthetic halogenated inhaled glucocorticoid. It is used for treating steroid-dependent asthma, for relieving symptoms associated with allergic or nonallergic (vasomotor) rhinitis, for preventing recurrent nasal polyps following surgical removal, and for the treatment of chronic obstructive pulmonary disease (COPD).

The antiinflammatory and vasoconstrictive effects of intranasal beclomethasone are 5,000 times greater than those produced by hydrocortisone.

Asthma guidelines consider orally inhaled corticosteroids (ICSs) to be the preferred pharmacologic treatment in the long-term management of persistent asthma.

The Expert Panel of the National Asthma Education and Prevention Program concluded that ICSs are the most potent and consistently effective class of medications for the long-term control of asthma in both adult and pediatric patients.

Superior efficacy of ICSs has been demonstrated over other long-term control medications including leukotriene receptor antagonists, cromolyn, and theophylline.

Indications

1. allergic rhinitis
2. asthma
3. chronic bronchitis
4. chronic obstructive pulmonary disease (COPD)
5. emphysema
6. exercise-induced bronchospasm prophylaxis
7. nasal polyps
8. perennial allergies
9. seasonal allergies
10. vasomotor rhinitis

Side Effects

1. adrenocortical insufficiency
2. anaphylactoid reactions
3. angioedema
4. anosmia
5. back pain
6. blurred vision
7. bronchospasm
8. candidiasis
9. cataracts
10. cough
11. Cushing’s syndrome
12. Cushingoid features
13. depression
14. dysgeusia
15. dysmenorrhea
16. dysphonia
17. eosinophilia
18. epistaxis
19. fever
20. growth inhibition
21. headache
22. hoarseness
23. hypothalamic-pituitary-adrenal (HPA) suppression
24. immunosuppression
25. increased intracranial pressure
26. infection
27. nasal dryness
28. nasal irritation
29. nasal septum perforation
30. nausea
31. ocular hypertension
32. osteopenia
33. osteoporosis
34. pharyngitis
35. purpura
36. rash
37. rhinitis
38. rhinorrhea
39. sinusitis
40. skeletal changes
41. sneezing
42. suicidal ideation
43. urticaria
44. visual impairment
45. wheezing
46. withdrawal
47. xerostomia

Monitoring Parameters

• pulmonary function tests (PFTs)

Contraindications

• abrupt discontinuation
• acute bronchospasm
• adrenal insufficiency
• breast-feeding
• cataracts
• children
• corticosteroid hypersensitivity
• Cushing’s syndrome
• depression
• diabetes mellitus
• fungal infection
• geriatric
• glaucoma
• growth inhibition
• hepatic disease
• herpes infection
• hyperglycemia
• hypothalamic-pituitary-adrenal (HPA) suppression
• increased intracranial pressure
• increased intraocular pressure
• infants
• infection
• malnutrition
• measles
• nasal septal perforation
• nasal surgery
• nasal trauma
• neonates
• ocular exposure
• osteoporosis
• paradoxical bronchospasm
• pregnancy
• psychosis
• status asthmaticus
• suicidal ideation
• surgery
• tobacco smoking
• tuberculosis
• varicella
• viral infection
• visual disturbance

Interactions

• Abatacept
• Acetaminophen; Aspirin, ASA; Caffeine
• Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
• Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
• Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
• Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
• Acetaminophen; Dextromethorphan; Phenylephrine
• Acetaminophen; Guaifenesin; Phenylephrine
• Acetazolamide
• Acetohexamide
• Adalimumab
• Albiglutide
• Aldesleukin, IL-2
• Alemtuzumab
• Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
• Aliskiren; Hydrochlorothiazide, HCTZ
• Alogliptin; Metformin
• Alpha-glucosidase Inhibitors
• Altretamine
• Ambenonium Chloride
• Amifampridine
• Amiloride; Hydrochlorothiazide, HCTZ
• Aminolevulinic Acid
• Aminosalicylate sodium, Aminosalicylic acid
• Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
• Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
• Amphotericin B
• Amphotericin B cholesteryl sulfate complex (ABCD)
• Amphotericin B lipid complex (ABLC)
• Amphotericin B liposomal (LAmB)
• Antithymocyte Globulin
• Antitumor antibiotics
• Argatroban
• Arsenic Trioxide
• Asparaginase Erwinia chrysanthemi
• Aspirin, ASA
• Aspirin, ASA; Butalbital; Caffeine
• Aspirin, ASA; Butalbital; Caffeine; Codeine
• Aspirin, ASA; Caffeine; Dihydrocodeine
• Aspirin, ASA; Caffeine; Orphenadrine
• Aspirin, ASA; Carisoprodol
• Aspirin, ASA; Carisoprodol; Codeine
• Aspirin, ASA; Citric Acid; Sodium Bicarbonate
• Aspirin, ASA; Dipyridamole
• Aspirin, ASA; Omeprazole
• Aspirin, ASA; Oxycodone
• Aspirin, ASA; Pravastatin
• Atenolol; Chlorthalidone
• Atracurium
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• Azathioprine
• Azilsartan; Chlorthalidone
• Basiliximab
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• Bendroflumethiazide; Nadolol
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• Calcium Carbonate; Simethicone
• Canagliflozin
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• Captopril; Hydrochlorothiazide, HCTZ
• Carbetapentane; Chlorpheniramine; Phenylephrine
• Carbetapentane; Diphenhydramine; Phenylephrine
• Carbetapentane; Guaifenesin; Phenylephrine
• Carbetapentane; Phenylephrine
• Carbetapentane; Phenylephrine; Pyrilamine
• Carbinoxamine; Hydrocodone; Phenylephrine
• Carbinoxamine; Phenylephrine
• Carmustine, BCNU
• Chlophedianol; Guaifenesin; Phenylephrine
• Chlorambucil
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• Chlorpheniramine; Dextromethorphan; Phenylephrine
• Chlorpheniramine; Dihydrocodeine; Phenylephrine
• Chlorpheniramine; Hydrocodone; Phenylephrine
• Chlorpheniramine; Phenylephrine
• Chlorpropamide
• Chlorthalidone
• Chlorthalidone; Clonidine
• Choline Salicylate; Magnesium Salicylate
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• Codeine; Phenylephrine; Promethazine
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• Empagliflozin; Linagliptin
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• Hydrocodone; Phenylephrine
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• Methenamine; Sodium Acid Phosphate
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• Sodium Benzoate; Sodium Phenylacetate
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