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Aluminum Hydroxide and Magnesium Trisilicate Brand Names
Alenic Alka | Foaming Antacid | Gaviscon | Genaton
What is Aluminum Hydroxide and Magnesium Trisilicate
Aluminum hydroxide and magnesium trisilicate is an oral combination product used as an antacid for temporary relief of symptoms associated with gastric acidity.
The side effects of constipation from aluminum and diarrhea from magnesium are dose related, and the combination of aluminum hydroxide and magnesium trisilicate allows for a potent acid neutralizing capacity with lower doses of each agent.
Aluminum and magnesium combinations are the most commonly used commercial antacids.
Aluminum hydroxide; magnesium trisilicate is commercially available in an oral tablet form and also contain the ingredient alginic acid.
Alginic acid creates a viscous foam barrier that floats on the top of stomach contents and is purported to be useful in gastroesophageal reflux, although the FDA considers alginic acid to be of questionable value. Gaviscon(R) tablets were approved by the FDA in 1972.
Indications
- dyspepsia
- gastroesophageal reflux disease (GERD)
- pyrosis (heartburn)
Side Effects
- anorexia
- constipation
- dehydration
- diarrhea
- diuresis
- encephalopathy
- GI obstruction
- hemorrhoids
- hypercalcemia
- hypermagnesemia
- hypophosphatemia
- hypotension
- impaired cognition
- malaise
- nausea
- nephrolithiasis
- osteomalacia
- osteoporosis
- vomiting
- weakness
Monitoring Parameters
- serum magnesium
Contraindications
- ascites
- breast-feeding
- children
- colostomy
- constipation
- diarrhea
- diverticulitis
- fecal impaction
- geriatric
- GI bleeding
- GI obstruction
- heart failure
- hemorrhoids
- hepatic disease
- hypermagnesemia
- hypophosphatemia
- ileostomy
- ileus
- infants
- neonates
- pregnancy
- renal disease
- renal failure
- renal impairment
Interactions
- Abacavir; Dolutegravir; Lamivudine
- Acalabrutinib
- Acetaminophen
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Codeine
- Acetaminophen; Dextromethorphan
- Acetaminophen; Dextromethorphan; Doxylamine
- Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
- Acetaminophen; Dextromethorphan; Phenylephrine
- Acetaminophen; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Dichloralphenazone; Isometheptene
- Acetaminophen; Diphenhydramine
- Acetaminophen; Guaifenesin; Phenylephrine
- Acetaminophen; Hydrocodone
- Acetaminophen; Oxycodone
- Acetaminophen; Pentazocine
- Acetaminophen; Propoxyphene
- Acetaminophen; Pseudoephedrine
- Acetaminophen; Tramadol
- Acidifying Agents
- Acrivastine; Pseudoephedrine
- Alendronate; Cholecalciferol
- Allopurinol
- Amlodipine; Atorvastatin
- Amphetamines
- Amprenavir
- Anticholinergics
- Ascorbic Acid, Vitamin C
- Atazanavir
- Atazanavir; Cobicistat
- Atenolol
- Atenolol; Chlorthalidone
- Atorvastatin
- Atorvastatin; Ezetimibe
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Azithromycin
- Baloxavir Marboxil
- Benzhydrocodone; Acetaminophen
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Bictegravir; Emtricitabine; Tenofovir Alafenamide
- Bisacodyl
- Bismuth Subcitrate Potassium; Metronidazole; Tetracycline
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Bisphosphonates
- Bosutinib
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Brompheniramine; Pseudoephedrine
- Budesonide
- Budesonide; Formoterol
- Calcium; Vitamin D
- Capecitabine
- Captopril
- Captopril; Hydrochlorothiazide, HCTZ
- Carbetapentane; Pseudoephedrine
- Carbinoxamine; Dextromethorphan; Pseudoephedrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Carbinoxamine; Pseudoephedrine
- Cardiac glycosides
- Cefdinir
- Cefditoren
- Cefpodoxime
- Cefuroxime
- Cetirizine; Pseudoephedrine
- Chenodiol
- Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
- Chloroquine
- Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Pseudoephedrine
- Chlorpromazine
- Cholic Acid
- Ciprofloxacin
- Citric Acid; Potassium Citrate
- Citric Acid; Potassium Citrate; Sodium Citrate
- Citric Acid; Sodium Citrate
- Conjugated Estrogens; Bazedoxifene
- Dasatinib
- Deferasirox
- Deferiprone
- Delafloxacin
- Delavirdine
- Demeclocycline
- Desloratadine; Pseudoephedrine
- Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
- Dexmethylphenidate
- Dextromethorphan; Guaifenesin; Pseudoephedrine
- Dextromethorphan; Quinidine
- Diazepam
- Didanosine, ddI
- Diflunisal
- Dihydrocodeine; Guaifenesin; Pseudoephedrine
- Diphenhydramine; Naproxen
- Dirithromycin
- Dolutegravir
- Dolutegravir; Lamivudine
- Dolutegravir; Rilpivirine
- Doxycycline
- Eltrombopag
- Elvitegravir
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
- Emtricitabine; Rilpivirine; Tenofovir alafenamide
- Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
- Erdafitinib
- Ergocalciferol, Vitamin D2
- Erlotinib
- Esomeprazole; Naproxen
- Ethambutol
- Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
- Ethinyl Estradiol; Norethindrone; Ferrous fumarate
- Ethotoin
- Ezetimibe
- Ezetimibe; Simvastatin
- Fexofenadine
- Fexofenadine; Pseudoephedrine
- Fosamprenavir
- Fosinopril
- Fosinopril; Hydrochlorothiazide, HCTZ
- Gabapentin
- Gastrointestinal Enzymes
- Gefitinib
- Gemifloxacin
- Glipizide
- Glipizide; Metformin
- Glyburide
- Glyburide; Metformin
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Guaifenesin; Pseudoephedrine
- Halofantrine
- Hydrochlorothiazide, HCTZ; Propranolol
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Hydroxychloroquine
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Ibuprofen; Pseudoephedrine
- Indomethacin
- Iron
- Iron Salts
- Isoniazid, INH; Pyrazinamide, PZA; Rifampin
- Isoniazid, INH; Rifampin
- Itraconazole
- Ketoconazole
- Lactulose
- Lansoprazole; Naproxen
- Ledipasvir; Sofosbuvir
- Lesinurad; Allopurinol
- Levofloxacin
- Levothyroxine
- Levothyroxine; Liothyronine (Porcine)
- Levothyroxine; Liothyronine (Synthetic)
- Liothyronine
- Loratadine; Pseudoephedrine
- Magnesium Citrate
- Mefenamic Acid
- Mefloquine
- Mesalamine, 5-ASA
- Methenamine
- Methenamine; Sodium Acid Phosphate
- Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
- Methylphenidate
- Minocycline
- Moxifloxacin
- Mycophenolate
- Naproxen
- Naproxen; Pseudoephedrine
- Naproxen; Sumatriptan
- Neratinib
- Nilotinib
- Nitrofurantoin
- Norfloxacin
- Ofloxacin
- Omadacycline
- Pancrelipase
- Pazopanib
- Penicillamine
- Pexidartinib
- Phenytoin
- Phosphorus
- Polyethylene Glycol; Electrolytes; Bisacodyl
- Polysaccharide-Iron Complex
- Ponatinib
- Potassium Bicarbonate
- Potassium Chloride
- Potassium Citrate
- Propranolol
- Pseudoephedrine
- Quinidine
- Quinine
- Raltegravir
- Rifampin
- Rilpivirine
- Riociguat
- Rosuvastatin
- Sarecycline
- Sodium Ferric Gluconate Complex; ferric pyrophosphate citrate
- Sodium Fluoride
- Sodium Polystyrene Sulfonate
- Sofosbuvir; Velpatasvir
- Sofosbuvir; Velpatasvir; Voxilaprevir
- Sotalol
- Sucralfate
- Tacrolimus
- Tetracycline
- Thyroid hormones
- Ticlopidine
- Tipranavir
- Trospium
- Ursodeoxycholic Acid, Ursodiol
- Valproic Acid, Divalproex Sodium
- Vitamin D
- Vitamin D analogs
- Zalcitabine, ddC
