Au Kline Syndrome
Au Kline Syndrome: A Comprehensive Clinical Review Introduction Au-Kline syndrome (AKS), also known as Okamoto syndrome, is a rare autosomal dominant neurodevelopmental disorder first described in 2015 by Au et al. and subsequently refined through international collaborative efforts. This condition represents a complex multiple malformation syndrome characterized by distinctive facial features, moderate-to-severe intellectual disability, hypotonia, …