Cryptogenic Organizing Pneumonia What is meant by the term cryptogenic organizing pneumonia (COP) The term COP is applied when organizing pneumonia is present without a clear etiology. Clinically, COP is characterized by months of low-grade fevers, cough, and malaise. Symptoms and imaging features typically rapidly improve with corticosteroid administration, although relapses can occur in 50% of cases. …
Connective Tissue Disease Associated Vasculitis Vasculitis is defined by inflammatory leukocytes and subsequent necrosis of blood vessel walls that can eventually lead to tissue ischemia. When vasculitis is associated with a connective tissue disease (CTD), it is defined as a secondary vasculitis. The connective tissue diseases that most commonly cause vasculitis include rheumatoid arthritis (RA), …
Chronic Pruritis Chronic pruritus is defined as a generalized itching sensation lasting ≥6 wk in duration. Epidemiology & Demographics Incidence Symptoms of itch are common accounting for about 7 million, or about 1%, of all outpatient office visits in the U.S. per year. Prevalence Estimates of prevalence within the general population range from 8% to …
Chemotherapy Induced Nausea and Vomiting Chemotherapy-induced nausea and vomiting (CINV) refers to adverse emetic effects associated with the use of systemic therapies used in the treatment of cancer. There are five recognized subtypes: •Acute-phase CINV: Nausea and vomiting starting within 24 hr after receiving chemotherapy. •Delayed-phase CINV: Nausea and vomiting beginning or returning > 24 …
12 Interesting Facts of Cystic Fibrosis Cystic fibrosis is an autosomal recessive, multisystem disorder caused by pathologic variants in the CFTR (cystic fibrosis transmembrane conductance regulator) gene resulting in altered chloride and bicarbonate transport across many epithelial tissues Disease primarily affects the upper and lower airways, pancreas, gastrointestinal tract (eg, intestine, hepatobiliary system), reproductive organs, and …
Claudication Claudication refers to reproducible pain, fatigue, discomfort, or cramping due to vascular origin in a muscle group that is consistently induced by exertion and is relieved with rest. Claudication results from inadequate blood flow to the target muscle group, which is not able to meet increased metabolic demand, resulting in a supply-and-demand mismatch due to …
Chorea Chorea is the term used to describe brief movements that involve contiguous muscle groups. The term comes from the Greek word meaning dance. Synonyms Sydenham chorea Saint Vitus dance Epidemiology & Demographics Incidence No published data exist on the incidence of chorea in the U.S. Can affect any age and sex depending on the cause …