Hypercoagulable State Hypercoagulable state is an inherited or acquired condition associated with an increased risk of thrombosis. A classification of hypercoagulable state is described in the below table. Classification of Hypercoagulable State Hereditary Mixed Acquired Loss of Function Antithrombin deficiency Hyperhomocysteinemia Previous venous thromboembolism Protein C deficiency Obesity Pregnancy, puerperium Protein S deficiency Cancer Drug-induced: …
Interesting Facts of Herpes Gestationis Herpes gestationis (gestational pemphigoid, pemphigoid gestationis) is an autoimmune bullous condition caused by IgG antibodies directed primarily against BPAg2 (occasionally BPAg1), a structure necessary for adherence of the epidermis to the basement membrane zone. The clinical presentation of a pregnant or recently pregnant woman who presents with a sudden onset …
6 Interesting Facts of Hallux Valgus Hallux valgus is a common progressive forefoot deformity consisting of lateral deviation of the hallux (big toe) at the metatarsophalangeal joint accompanied by medial deviation of the first metatarsal (metatarsus primus varus) Great toe angulates away from midline and toward other toes Bony eminence at medial aspect of first …
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Hip Flexor and Groin Strain Hip flexor and groin (adductor) strains are common injuries in athletes, especially those in sports that involve kicking, cutting, and sprinting, such as soccer, football, and ice hockey. •Among soccer players, groin injuries account for 8–18% of all injuries. •A number of muscles are involved in flexion of the hip, …
Delayed Puberty Delayed puberty is clinically defined as the absence or incomplete development of secondary sexual characteristics by an age at which 95% of the population begins to mature sexually. 0For girls, a delay in puberty is defined as an absence of breast bud development by age 13 or absence of menarche within 3 yr …
8 Interesting Facts of Dehydration in Adults Dehydration is a term that refers to a reduction in total body water without a proportional reduction in sodium and potassium Dehydration (loss of free water) is distinct from volume depletion Most cases are caused by pure water losses from diabetes insipidus, insensible and sweat losses, osmotic diarrhea, …
8 Interesting Facts of DEET Toxicity N,N-diethyl-3-methylbenzamide (DEET) is a common insect repellent; potential toxicity may manifest with: Dermal reactions from topical application usually occur in association with products containing high DEET concentrations (greater than 50%) Neurotoxicity (eg, lethargy, seizures, toxic encephalopathy) with significant systemic absorption; most cases of serious systemic toxicity result from ingestion, …