Pirfenidone Brand Name– ESBRIET What is Pirfenidone Pirfenidone is an oral pyridone for the treatment of idiopathic pulmonary fibrosis. During randomized, double-blind, placebo-controlled trials, pirfenidone significantly reduced decline in forced vital capacity (FVC). Differences in mean decline in FVC over time between treatment groups ranged from 157 to 193 mL. All-cause mortality was not significantly …
Pirbuterol Brand Names- Maxair | Maxair Autohaler What is Pirbuterol Pirbuterol is an inhaled sympathomimetic bronchodilator agent. It is a relatively selective beta-2 receptor agonist and is structurally similar to albuterol. Pirbuterol is used to prevent or relieve reversible bronchospasm associated with acute and chronic bronchial asthma, exercise-induced bronchospasm, bronchitis, emphysema, bronchiectasis, or other obstructive pulmonary …
Piperacillin and Tazobactam Brand Name– Zosyn What is Piperacillin and Tazobactam Piperacillin and tazobactam are combined in a single intravenous formulation to provide a broad spectrum of activity. Piperacillin and tazobactam is commonly used to treat serious nosocomial infections that are often polymicrobial in nature. Piperacillin, a ureidopenicillin, is an extended-spectrum penicillin. Tazobactam, an irreversible …
What is Piperacillin Piperacillin is a parenteral, semisynthetic, extended-spectrum acylureidopenicillin. Extended-spectrum penicillins, such as piperacillin, are used mainly in the treatment of serious, gram-negative infections and in combination with an aminoglycoside to treat systemic Pseudomonas infections. Clinically, piperacillin is used to treat intra-abdominal infections, respiratory and urinary tract infections, skin and soft-tissue infections, and other infections caused …
What is Pipecuronium NOTE: This drug is discontinued in the US. Pipecuronium is a long-acting, nondepolarizing, neuromuscular blocker, which is structurally related to pancuronium. It is used to cause skeletal muscle relaxation as an adjunct to general anesthesia or for endotracheal intubation. The use of pipecuronium in clinical practice has been limited by its long …
Pioglitazone Brand Name– Actos What is Pioglitazone Pioglitazone is an oral antidiabetic agent of the thiazolidinedione (TZD) class, also called ‘insulin sensitizers.’ Pioglitazone is approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 DM (DM) and is given once daily. The TZDs specifically target insulin resistance that …
What is Pindolol Pindolol is an oral, nonselective, beta-receptor antagonist with intrinsic sympathomimetic activity (ISA) (i.e., partial agonist activity). Pindolol is the beta-blocker with the highest degree of ISA and nonselective antagonist qualities. The effect of ISA, as with beta-blockade in general, can be selective or nonselective in nature. The partial agonist potential of pindolol …