Amphetamine Derivatives Toxicity – 7 Interesting Facts Alarm Signs and Symptoms Introduction Background Information Table 1. Characteristics of specific amphetamine derivatives. Amphetamine derivative Street names1 Toxicodynamics Noteworthy adverse effects Methamphetamine Crank Crystal Glass Ice Meth Speed Yaba Structure is lipophilic, conferring greater CNS activity and resistance to degradation by monoamine oxidase1 Cardiomyopathy and CAD78Dental caries and …
Acute Iron Toxicity – Urgent Action 8 Interesting Facts of Acute Iron Toxicity Pitfalls Terminology Clinical Clarification Classification Diagnosis Clinical Presentation 3 History Table Amount of elemental iron in various formulations. Formulation Percentage of elemental iron Amount of elemental iron per dose Ferrous fumarate 33 65 mg in 200-mg tablet Ferrous sulfate 20 60 mg in 300-mg …
Tricyclic Antidepressant Overdose Synonyms Epidemiology & Demographics How common is this condition? Selected Drug Interactions With Tricyclic Antidepressants From Stern TA et al: Massachusetts General Hospital handbook of general hospital psychiatry, ed 7, Philadelphia, 2018, Elsevier. Drug Potential Interaction Carbamazepine Decreased TCA plasma levels Phenobarbital Rifampin Isoniazid Antipsychotics Increased TCA plasma levels Methylphenidate SSRIs Quinidine …
16 Interesting Facts of Calcium Channel Blocker Toxicity Calcium channel blocker toxicity may cause vasodilation, decreased inotropy (ie, contractility), decreased dromotropy (ie, conduction), and/or decreased chronotropy (ie, heart rate); overdose is characterized by hypotension, bradycardia, and potentially death Toxicity may occur after intentional or accidental overdose; calcium channel blockers are associated with highest risk of fatality …
3 Interesting Facts of NSAID Associated Gastritis Histologically, gastritis refers to inflammation in the stomach. Endoscopically, gastritis refers to a number of abnormal features such as erythema, erosions, and subepithelial hemorrhages. Gastritis can also be subdivided into erosive, nonerosive, and specific types of gastritis with distinctive features both endoscopically and histologically. •Most nonsteroidal antiinflammatory drugs (NSAIDs) currently …
Gastrointestinal Issues Associated With Psychiatric Medications Etiology & Risk Factors Drugs reported to cause problems in the oesophagus, together with their proposed mechanisms Presentation Putative mechanisms Drugs commonly reported Pill oesophagitis Hold-up in clearance of the pill from the oesophagitisCaustic injury of locally released drug TetracyclinesBisphosphonatesPotassium chlorideNSAIDsIron Gastroesophageal reflux Lower oesophageal sphincter pressure NitratesCalcium channel …
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Acetaminophen Toxicity – 14 Interesting Facts Acetaminophen toxicity can be classified as acute (one-time single ingestion) or chronic (repeated supratherapeutic ingestions); most common cause of acute liver failure in the United States Acetaminophen is primarily toxic to the liver but can cause dysfunction of other organ systems such as renal system, central nervous system, and metabolic system …