Alfentanil Brand Name– Alfenta What is Alfentanil Alfentanil is a synthetic opiate agonist that is used primarily in anesthesia. Alfentanil is a member of the phenylpiperidine class of opiate agonists and is a derivative of fentanyl. Alfentanil has significantly different pharmacokinetics and pharmacodynamics than fentanyl or sufentanil. Fentanyl is 5—8 times more potent than alfentanil. …
Alendronate and Cholecalciferol Brand Name– Fosamax Plus D What is Alendronate and Cholecalciferol Alendronate and cholecalciferol is a combination product used once per week to increase bone mass and treat osteoporosis in both men and postmenopausal women. Alendronate is a second-generation bisphosphonate, and such bisphosphonates are generally considered to be first-line therapy for the treatment …
Alendronate Brand Names- Binosto | Fosamax What is Alendronate Alendronate is an oral second-generation bisphosphonate; weekly or daily regimens are available for selected conditions. Treatment with alendronate is associated with significant increases in bone mineral density (BMD) and reduces the risk for radiographic vertebral and non-vertebral fractures (e.g., hip fractures) in postmenopausal women. Bisphosphonates such as …
Alemtuzumab Brand Names – Campath | LEMTRADA What is Alemtuzumab Alemtuzumab is a humanized monoclonal antibody directed against the CD52 antigen. The CD52 antigen is expressed on the surface of normal and malignant B-lymphocytes, T-lymphocytes, NK cells, monocytes, macrophages, platelets, and tissues of the male reproductive system; the CD52 antigen is not expressed on hemopoietic stem …
Alefacept Brand Name– Amevive What is Alefacept NOTE: This drug is discontinued in the U.S. Alefacept was a recombinant human leukocyte-function-associated antigen type 3 (LFA-3)/IgG1 fusion protein. Alefacept, a 91.4 kDa glycosylated protein, is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) cell expression system. It possesses immunomodulatory and immunosuppressive effects. Alefacept …
Alectinib Brand Name– Alecensa What is Alectinib Alectinib is a tyrosine kinase inhibitor that targets ALK and RET. It is used for the treatment of patients with ALK-positive, metastatic non-small cell lung cancer (NSCLC). Common adverse effects include fatigue, constipation, edema, myalgia, and anemia; serious adverse reactions include hepatotoxicity, pneumonitis, bradycardia, and elevated creatine phosphokinase …
Aldesleukin Brand Name– Proleukin What is Aldesleukin Aldesleukin is recombinant formulation of interleukin-2 (IL-2). Aldesleukin is a nonglycosylated biosynthetic interleukin-2 (also known as T-cell growth factor), which differs only slightly in amino acid sequence from the natural compound. Interleukins function as molecular messengers between leukocytes. Given in its original dosing scheme as listed in the …