Where are brain metastases usually located in the brain?
Eighty percent are located in the cerebral hemispheres, 15% in the cerebellum, and 5% in the brainstem.
This distribution correlates with the blood flow to each area of the brain as the most common mechanism of metastasis to the brain is by hematogenous spread.
Brain metastases tend to develop in “watershed” areas where the vasculature is narrow as well as at the gray–white matter junctions.