Manifestations of lupus that warrant high dose prednisone ≥1 mg/kg/day corticosteroid therapy

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Manifestations of lupus that warrant high dose prednisone ≥1 mg/kg/day corticosteroid therapy

• Severe lupus nephritis

• CNS lupus with severe manifestations (including transverse myelitis)

• Autoimmune thrombocytopenia with extremely low platelet counts (e.g., <30,000/mm )

• AIHA

• Acute pneumonitis

• Diffuse alveolar hemorrhage

• Severe vasculitis with visceral organ involvement

• Serious complications from pleuritis, pericarditis, or peritonitis

• MAS

Other SLE manifestations should be able to be controlled with lower doses of prednisone.

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